Vitamin D
Vitamin D regulates the absorption of calcium and phosphorus, facilitates a normal immune system, promotes cardiovascular health, supports weight loss, and regulates insulin levels which supports diabetes prevention and management.
1,25-Dihydroxyvitamin D Protects Against Age-Related Osteoporosis by a Novel VDR-Ezh2-p16 Signal Axis. Aging cell. https://www.ncbi.nlm.nih.gov/pubmed/31880094
Vitamin D deficiency accelerates ageing and age-related diseases: a novel hypothesis. J Physiol. https://www.ncbi.nlm.nih.gov/pubmed/28949008
Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases. Sci Rep. https://www.ncbi.nlm.nih.gov/pubmed/29769621
Vitamin D Receptor Genotype, Vitamin D3 Supplementation, and Risk of Colorectal Adenomas.JAMA Oncology https://jamanetwork.com/journals/jamaoncology/fullarticle/2593044?resultClick=1
Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis. A Review.JAMA Neurology https://jamanetwork.com/journals/jamaneurology/article-abstract/2679039?resultClick=1
Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years. The VDAART Randomized Clinical Trial.JAMA https://jamanetwork.com/journals/jama/fullarticle/2484339
1,25-Dihydroxyvitamin D Protects Against Age-Related Osteoporosis by a Novel VDR-Ezh2-p16 Signal Axis.Aging cell https://www.ncbi.nlm.nih.gov/pubmed/31880094
Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial.The Journal of Allergy and Clinical Immunology https://www.jacionline.org/article/S0091-6749(17)30575-4/fulltext
Vitamin D Status During Pregnancy and Risk of Multiple Sclerosis in Offspring of Women in the Finnish Maternity Cohort.JAMA Neurology https://jamanetwork.com/journals/jamaneurology/fullarticle/2499458
Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality.A Systematic Review and Meta-analysis.JAMA Pediatrics https://jamanetwork.com/journals/jamapediatrics/fullarticle/2681636?resultClick=1
Vitamin D supplementation for women during pregnancy.Cochrane Database of Systematic Reviews https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008873.pub4/full?highlightAbstract=d%7Cvitamine%7Cvitamin
High Doses of Vitamin D to Reduce Exacerbations in Chronic Obstructive Pulmonary Disease: A Randomized Trial.Annals of Internal Medicine https://annals.org/aim/fullarticle/1033290/high-doses-vitamin-d-reduce-exacerbations-chronic-obstructive-pulmonary-disease?searchresult=1
Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction.New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa1906137
Vitamin D supplementation for prevention of mortality in adults.Cochrane Database of Systematic Reviews https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007470.pub3/full?highlightAbstract=d%7Cvitamine%7Cvitamin
Effects of Vitamin D Supplementation on Muscle Strength in Athletes: A Systematic Review.J Strength Cond Res https://www.ncbi.nlm.nih.gov/pubmed/27379960
Vitamin D Deficiency: Effects on Oxidative Stress, Epigenetics, Gene Regulation, and Aging.Biology (Basel) https://www.ncbi.nlm.nih.gov/pubmed/31083546
Vitamin D levels correlate with lymphocyte subsets in elderly patients with age-related diseases.Sci Rep https://www.ncbi.nlm.nih.gov/pubmed/29769621
25-Hydroxyvitamin D3 positively regulates periodontal inflammaging via SOCS3/STAT signaling in diabetic mice.Steroids https://www.ncbi.nlm.nih.gov/pubmed/31917967
Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor (BDNF).Nutr Neurosci https://www.ncbi.nlm.nih.gov/pubmed/31524100
Serum Vitamin D and Age-Related Muscle Loss in Afro-Caribbean Men: The Importance of Age and Diabetic Status.J Frailty Aging https://pubmed.ncbi.nlm.nih.gov/31237313/
Vitamin D in Relation to Incident Sarcopenia and Changes in Muscle Parameters Among Older Adults: The KORA-Age Study.Calcif Tissue Int https://pubmed.ncbi.nlm.nih.gov/31069442
Age-dependent expression of the vitamin D receptor and the protective effect of vitamin D receptor activation on H2O2-induced apoptosis in rat intervertebral disc cells.J Steroid Biochem Mol Biol https://www.ncbi.nlm.nih.gov/pubmed/30905826
Age-related deterioration of saccule-related neural function is associated with decreased estimated glomerular filtration rate and increased free thyroxine.Prostate https://pubmed.ncbi.nlm.nih.gov/29508414/
Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci https://pubmed.ncbi.nlm.nih.gov/28892825
Vitamin D Improves Neurogenesis and Cognition in a Mouse Model of Alzheimer’s Disease.Mol Neurobiol https://pubmed.ncbi.nlm.nih.gov/29318446-vitamin-d-improves-neurogenesis-and-cognition-in-a-mouse-model-of-alzheimers-disease/?from_term=vitamin+d+and+alzheimer&from_pos=2
Vitamin D and the Risk of Dementia and Alzheimer Disease.Neurology https://pubmed.ncbi.nlm.nih.gov/25098535-vitamin-d-and-the-risk-of-dementia-and-alzheimer-disease/?from_term=vitamin+d+and+alzheimer&from_pos=4
A Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas.New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa1500409
Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease.New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa1809944
Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers.JAMA https://jamanetwork.com/journals/jama/fullarticle/2730111?resultClick=1
Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women.JAMA https://jamanetwork.com/journals/jama/fullarticle/2613159?resultClick=1
Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth.New England Journal of Medicine https://www.nejm.org/doi/full/10.1056/NEJMoa1800927
Effect of Vitamin D and Omega-3 Fatty Acid Supplementation on Kidney Function in Patients With Type 2 Diabetes. A Randomized Clinical Trial.JAMA https://jamanetwork.com/journals/jama/article-abstract/275530
Effect of vitamin D on bone strength in older African Americans: a randomized controlled trial.J Nutr Health Aging https://www.ncbi.nlm.nih.gov/pubmed/31938818
Vitamin D Status and Prevalent Early Age-Related Macular Degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study.J Nutr Health Aging https://pubmed.ncbi.nlm.nih.gov/28717807-vitamin-d-status-and-prevalent-early-age-related-macular-degeneration-in-african-americans-and-caucasians-the-atherosclerosis-risk-in-communities-aric-study/
Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults.JAMA https://jamanetwork.com/journals/jama/fullarticle/2667071?resultClick=1
Effect of Vitamin D Supplementation on Progression of Knee Pain and Cartilage Volume Loss in Patients With Symptomatic Osteoarthritis
A Randomized Controlled Trial.JAMA https://jamanetwork.com/journals/jama/fullarticle/1556148?resultClick=1
Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 83 000 Individuals in 21 Randomized Clinical Trials. A Meta-analysis.JAMA Cardiology https://jamanetwork.com/journals/jamacardiology/article-abstract/2735646
Effect of Vitamin D Supplementation on Blood Pressure.A Systematic Review and Meta-analysis Incorporating Individual Patient Data.JAMA Internal Medicine https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2195120?resultClick=1
Vitamin D for the management of multiple sclerosis.Cochrane Database of Systematic Reviews https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008422.pub3/full?highlightAbstract=d%7Cvitamine%7Cvitamin
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